Department of Medicine

Team Work

The Best of Care

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Research

The Jacobi Department of Medicine's close affiliation with the Albert Einstein College of Medicine affords many opportunities for research. Clinical or laboratory research projects are generally undertaken during elective time in the second year of fellowship. In addition our fellows are provided opportunities for research at Columbia Presbyterian Hospital.

Our fellows have been able to perform high quality research with nationally and internationally recognized experts in Nephrology.

All our fellows have presented their work at the national meetings such as the American Society of Nephrology and the National Kidney Foundation. In addition, our fellows have authored papers in top ranking scientific journals. They have been winners at the "Fellows' Night " held at Cornell University Medical Center by the New York Society of Nephrology.

On the Jacobi campus, the new Price Center for Translational and Molecular Biology Research is evidence of Einstein's continuing commitment to excellence in Medical Research.

Investigator-Initiated Research topics include:

  • Improving care of the patient with chronic kidney disease (CKD)
  • Improving care of the new dialysis patient
  • Vitamin D and sepsis
  • Epidemiology of Acute Kidney Injury (AKI)
  • Preeclampsia
  • Urinary biomarkers in diabetic renal disease

  • Urinary biomarkers in hepatorenal disease 

Landmark mutlicenter trials include:

  •  Trial to Reduce Cardiovascular Events with Aranesp Therapy-TREAT Trial using darbepoetin alpha in CKD patients

  •  Registry of patients with secondary hyperparathyroidism in Chronic Kidney Disease

  • A multicentre, randomized, double-blind, parallelgroup, phase IV study to compare the renal effects of a non-ionic iso-osmolar contrast medium iodixanol 320 mgl/ml(VisipaqueTM) with a non-ionic low osmolar contrast medium iopamidol 370 mgl/ml) 

  • Pharmacoeconomic Evaluation (Time and Motion) Comparing RO0503821 to Epoetin Alfa in Patients with Chronic Kidney Disease (CKD) Stage V On Dialysis

  • A randomized, single blind trial to assess the effectiveness of maintaining patency and safety of the vascular wrap™ Paclitaxel-eluting mesh after surgical implantation with the Lifespan® PTFE vascular graft in the upper extremity for hemodialysis vascular access

  • A phase IIIb, randomized, double-blind, parallel group, multi-center, study to assess the efficacy and safety of multiple 30 minute infusions of Conivaptan in subjects with euvolemic or hypervolemic hyponatremia.

  • A multi center study using Lanthanum Carbonate as treatment for hyperparathyroidism in E.S.R.D patients - F.E.A.T.U.R.E Trial

  • A phase 3, Randomized controlled, Open label, multi center Study of the safety and efficacy of AF37702 Injection for the maintenance treatment of anemia in hemodialysis patients previously treated with Epoetin alfa

  • An Observer-Blinded, Randomized Study Comparing the Safety and Immunogenicity of HEPLISAVTM  to Licensed Vaccine (Energix-B®)  among Adults (18-70 Years of Age) with Chronic Kidney Disease (CKD)

 

 Ongoing Clinical Trials: 

  •               Dialysis Registry
  •               Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes
  •               DPP4 inhibitor in DM/CKD